Education

  • Ph.D. Cardiovascular Physiology and Health - Cardiff Metropolitan University, Cardiff, UK - 2015/20
  • MSc Cardiovascular Science - University College London, London, UK - 2014/15
  • BSc (Hons.) Sport and Exercise Science - University of South Wales, Pontypridd, UK - 2011/14

Contact Information

Denis J Wakeham., Ph.D.
Post-doctoral Research Fellow,
Cardiovascular Physiology Autonomic FunctionLaboratory
Institute for Exercise and Environmental Medicine
Texas Health Presbyterian Dallas
7232 Greenville Avenue, Dallas, TX 75231
Office: 214-345-4658
Fax: 214-345-4618
Email: DenisWakeham@texashealth.org

Highlighted Publications
  • Total haemoglobin mass, but not haemoglobin concentration, is associated with preoperative cardiopulmonary exercise testing-derived oxygen-consumption variables

    Otto, J. M., Plumb, J. O. M., Wakeham, D., Clissold, E., Loughney, L., Schmidt, W., Montgomery, H. E., Grocott, M. P. W. & Richards, T. (2017) Total haemoglobin mass, but not haemoglobin concentration, is associated with preoperative cardiopulmonary exercise testing-derived oxygen-consumption variables. Br J Anaesth, 118, 747-754. PMID: 28510737

  • Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia

    Otto, J. M., Plumb, J. O. M., Clissold, E., Kumar, S. B., Wakeham, D. J., Schmidt, W., Grocott, M. P. W., Richards, T. & Montgomery, H. E. (2017) Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia. Haematologica, 102, 1477-1485. PMID: 28596281

  • Carotid artery wall mechanics in young males with high cardiorespiratory fitness

    Pugh, C. J. A., Stone, K. J., Stohr, E. J., Mcdonnell, B. J., Thompson, J. E. S., Talbot, J. S., Wakeham, D. J., Cockcroft, J. R. & Shave, R. (2018). Carotid artery wall mechanics in young males with high cardiorespiratory fitness. Exp Physiol, 103, 1277-1286. PMID: 29959801

  • Upward resetting of the vascular sympathetic baroreflex in middle-aged runners

    Wakeham, D. J., Lord, R. N., Talbot, J. S., Lodge, F. M., Curry, B. A., Dawkins, T. G.,
    Simpson, L. L. S., Shave, R., Pugh, C. J. A. & Moore, J. P. (2019). Upward resetting of the vascular sympathetic baroreflex in middle-aged runners. American Journal of Physiology – Heart & Circulatory Physiology 317, H181-H189. PMID: 31050557

  • Acute intermittent hypercapnic hypoxia and sympathetic neurovascular transduction in men

    Stuckless, T. J. R., Vermeulen, T. D., Brown, C. V., Boulet, L. B., Shafer, B. M.,
    Wakeham, D. J., Steinback, C. D., Ayas, N. T., Floras, J. S. & Foster, G. E. (2020). Acute intermittent hypercapnic hypoxia and sympathetic neurovascular transduction in men. J Physiol. PMID: 31805605
    - Featured in a Journal Club Article - PMID: 32022925
    - Winner of the Early Career Investigator Prize for the Cardiovascular category in the Journal of Physiology - https://physoc.onlinelibrary.wiley.com/hub/journal/14697793/features/early-investigator-prize

  • The influence of habitual endurance exercise on carotid artery strain and strain rate in young and middle-aged men

    Talbot, J. S., Lord, R. N., Wakeham, D. J., Dawkins, T. G., Curry, B. A., Brown, M.,
    Lodge, F. M. & Pugh, C. J. A. (2020). The influence of habitual endurance exercise on carotid artery strain and strain rate in young and middle-aged men. Exp Physiol, 105, 1396-1407. PMID: 32578897

  • The influence of barosensory vessel mechanics on the vascular sympathetic baroreflex: insights into ageing and blood pressure homeostasis

    Lord, R. N., Wakeham, D. J., Talbot, J. S., Simpson, L. L. S., Curry, B. A., Pugh, C. J. A., Shave, R., & Moore, J. P. (2020). The influence of barosensory vessel mechanics on the vascular sympathetic baroreflex: insights into ageing and blood pressure homeostasis. Am J Physiol Heart Circ Physiol 319(2): H370-H376. PMID: 32648822

  • Distinct contributions of skin and core temperatures to flow-mediated dilation of the brachial artery following passive heating

    Coombs, G. B., Tremblay, J. C., Shkredova, D. A., Carr, J. M. J. R., Wakeham, D. J.,
    Patrician, A., & Ainslie, P. N. (2020). Distinct contributions of skin and core temperatures to flow-mediated dilation of the brachial artery following passive heating. J Appl Physiol (1985). PMID: 33119469

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