Open Studies
- Cooling Modalities, Burn Survivors, Exercise
- COPD, Heat Wave, Aging, and Cardiovascular Function
- Cooling Modalities, Heat Wave, Aging, Cardiovascular Function
- Skin Temperature, Epidermal, Subdermal
- Steven-Johnson Syndrome, Toxic Epidermal Necrolysis, Thermoregulation
- Beta Blockers, Cardiovascular Function, Thermoregulation
Cooling Modalities, Burn Survivors, Exercise
(IRB STU-2020-0334)
Purpose
The purpose of this study is to examine the effect of skin wetting on core and skin temperatures in burn survivors.
Eligibility
- >18 years of age
- No known heart disease
- Free from chronic medical conditions requiring regular medical therapy including cancer or diabetes
- Controlled systolic BP <140 mmHg and diastolic BP <90 mmHg
- Non-smoker or has not smoked regularly in the past 3 years
- Not taking tricyclic antidepressants, loop diuretics, centrally acting calcium channel blockers, or beta-blockers
- BMI <35 BMI Calculator
Study timeline
Participation requires two study visits lasting up to ~6 hours in total. Qualified participants will be compensated.
Contact Information
If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-5022.
COPD, Heat Wave, Aging, and Cardiovascular Function
(IRB STU# 2019-1759)
Purpose
The purpose of this study is to assess the cardiovascular responses of older individuals with COPD during exposure to heat wave conditions.
Eligibility
- >60 years of age
- Currently diagnosed with COPD
- No chronic medical conditions (other than COPD) requiring regular medical therapy such as cancer or diabetes
- Not currently taking medications involving centrally acting calcium channel blockers or beta-blockers
- BMI <35 BMI Calculator
Study timeline
Participation requires up to four study visits lasting up to ~21 hours in total. Qualified participants will be compensated.
Contact Information
If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-5022.
Cooling Modalities, Heat Wave, Aging, Cardiovascular Function
(IRB STU# 2022-0625)
Purpose
The purpose of this study is to examine the effect of cooling modalities on the physiological response of older individuals during controlled heat stress.
Eligibility
- >65 years of age
- No known heart disease
- Free from chronic medical conditions requiring regular medical therapy including cancer or diabetes
- Controlled systolic BP <140 mmHg and diastolic BP <90 mmHg
- Controlled total cholesterol of <200 mg/dl
- Non-smoker or has not smoked regularly in the past 3 years
- Not taking tricyclic antidepressants, loop diuretics, centrally acting calcium channel blockers, or beta-blockers
- Body mass index <31 (BMI Calculator)
Study timeline
Participation requires up to five study visits lasting up to ~30 hours in total. Qualified participants will be compensated.
Contact Information
If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-5022.
Skin Temperature, Epidermal, Subdermal
Purpose
The purpose of this study is to examine the effect of skin wetting on core and skin temperatures in burn survivors.
Eligibility
- >18 years of age
- No known heart disease
- Free from chronic medical conditions requiring regular medical therapy including cancer or diabetes
- Controlled systolic BP <140 mmHg and diastolic BP <90 mmHg
- Non-smoker or has not smoked regularly in the past 3 years
- Not taking tricyclic antidepressants, loop diuretics, centrally acting calcium channel blockers, or beta-blockers
- BMI <35 BMI Calculator
Study timeline
Participation requires two study visits lasting up to ~6 hours in total. Qualified participants will be compensated.
Contact Information
If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-5022.
Steven-Johnson Syndrome, Toxic Epidermal Necrolysis, Thermoregulation
Purpose
The purpose of this project is to identify the consequence of Stevens-Johnson Syndrome (SJS) on neural control of skin blood flow and sweating.
Eligibility
- 18-70 years old
- Experienced a case of healed Stevens-Johnson Syndrome and/or Toxic Epidermal Necrolysis.
- Free of any significant underlying medical problems based upon a detailed medical history and physical exam
- Body Mass Index < 35 kg/m2
- Not pregnant or planning to become pregnant within the subsequent 6 months.
Study timeline
Participation requires one study visit lasting up to ~4 hours in total. Qualified participants will be compensated.
Contact Information
If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-5022.
Beta Blockers, Cardiovascular Function, Thermoregulation
Purpose
To determine if the drugs propranolol and metoprolol result in greater increases in core body temperature during 3 hours of heat wave conditions in older adults.
Eligibility
- English speaking
- 65+ years of age
- No current or previous history of cancer, cardiac, respiratory, neurological, or metabolic illness
- Not pregnant or breast feeding
- Not a current smoker or smoked regularly in the past 3 years
- BMI < 30 kg/m2
Study timeline
Participation requires 3 study visits lasting up to ~20 hours in total. Qualified participants will be compensated.
Contact Information
If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-5022.